Artemisinin is a sesquiterpene lactone isolated from the aerial part of sweet wormwood in the 1970s. It is the base for one of the most effective medicines for the treatment of malaria and is widely used. Over the past two decades many in vitro and in vivo studies have been conducted with artemisinin. They detected the anticancer properties of this drug in relation to some cancer cell lines.
The aim of the study was to review the scientific information on the study of clinical cases and the results of clinical trials with the use of drugs based on artemisinin derivatives.
The study used information retrieval and library databases, as well as ResearchGate applications for semantic search.
During the study, it was found that most of the known clinical cases and performed clinical studies are associated with the study of the anticancer properties of one of the artemisinin derivatives – artesunate.
The data obtained by various research groups at the moment does not allow us to speak to the pronounced properties of the latter. However, the facts of extending the life of patients, improving its quality, and increasing control over the disease have been established.
It can be concluded that the published data of clinical cases and clinical studies conducted from 2001 to 2016 instill restrained optimism associated with the prospect of using drugs based on artemisinin in oncology.
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